Polystyrene-degrading bacteria modulate host stress and toxicity responses to microplastic exposure in Caenorhabditis elegans
Jun 10, 2026 l Hit 244
o A research team led by Professor Younghoon Kim in the Department of Agricultural Biotechnology at Seoul National University's College of Agriculture and Life Sciences has identified a bacterial strain capable of converting cultivated-meat spent medium (CSM) into a biodegradable bioplastic. CSM is generated after animal cells are cultured for cultivated meat production and contains residual organic carbon, nitrogen compoun...
Germ cell-directed exosomal delivery enables in vivo genetic modification in birds
May 4, 2026 l Hit 67
Avian embryos present substantial barriers to early-stage genetic manipulation due to avian physiology and opaque yolk, underscoring the need for alternative in vivo germline delivery systems. Extracellular vesicles (EVs), particularly exosomes, are biocompatible nanoscale carriers of nucleic acids, yet their potential for germline targeting in birds has not been investigated. Here, we isolated exosomes from long-term cultu...
Polystyrene-degrading bacteria modulate host stress and toxicity responses to microplastic exposure in Caenorhabditis elegans
Apr 16, 2026 l Hit 67
Metabolic dysfunction-associated steatohepatitis (MASH) represents a growing global health challenge due to its propensity to progress to irreversible hepatic disorders, including fibrosis, cirrhosis, and carcinoma. This study aimed to investigate the role of gut microbiota in the pathogenesis of MASH. We identified Romboutsia hominis as a key contributor to MASH progression, exacerbating hepatic lipid accumulation and infl...
Classification of honey types via flow profile analysis on μPAD combined with physicochemical characterization of honey–chitosan mixtures
Apr 2, 2026 l Hit 62
This study introduces a chitosan-based paper microfluidic platform that enhances flow-profile differences among honey types (sugar-fed, acacia, polyfloral, and chestnut). Using honey samples of each type collected from four geographical regions, distinct flow profiles were observed, with succinic acid identified as the key factor enabling honey type classification. Physicochemical characterization based on CLSM, DLS, zeta p...
Polystyrene-degrading bacteria modulate host stress and toxicity responses to microplastic exposure in Caenorhabditis elegans
Mar 23, 2026 l Hit 28
Researchers at Seoul National University demonstrated that the toxicity of microplastics can vary depending not only on particle properties but also on the bacterial strains present alongside them. Using Caenorhabditis elegans, the team showed that Enterobacter sp. LG3 aggravated physiological stress and intestinal accumulation of polystyrene microplastics, whereas Bacillus sp. SCGB1 alleviated these effects. The study furt...
Allelic variation at a single locus distinguishes spring and winter faba beans
Mar 16, 2026 l Hit 26
A multinational research team including Professor Tae-Jin Yang’s group at Seoul National University (Director of the Green Bio Science & Technology Institute and head of the BK21 Creative Leader Program for Agricultural and Forestry Bio-resources) and Dr. Soon-Jae Kwon’s team at the Korea Atomic Energy Research Institute has discovered that the winter survival of faba bean is determined by a single genomic l...
Unraveling the regioselectivity of Ophiostoma piceae sterol esterase as a case study for lipases with wide acyl-binding tunnel entrances
Mar 9, 2026 l Hit 27
SNU CALS team led by Prof. Pahn-Shick Chang has elucidated the structural mechanism underlying the sn-1(3) regioselectivity of OPE and established a comprehensive correlation between tunnel morphology and positional preference in lipases. By integrating chiral-phase resolution and molecular dynamics simulations, the team demonstrated how the width of tunnel entrance dictates catalytic orientation, providing structural insig...
Invisible partnerships beneath Tricholoma matsutake habitat: The hidden microbialsupportsystem in the soil
Jan 28, 2026 l Hit 30
BackgroundEctomycorrhizal (ECM) fungi establish symbiotic relationships with plant roots, enhancing nutrient uptake, improving plant health, and boosting ecosystem resilience. Although previous studies reported molecular interactions among plant-ECM fungi-surrounding microbes near plant roots, microbiome-wide metabolic shifts and associations with the fungi remain unclear.ResultsUsing Tricholoma matsutakeas a model, we init...
Seoul National University Researchers Present a Dual-Targeted Extracellular Vesicle–Based Immunotherapy Platform with Therapeutic Potential for Refractory Inflammatory Bowel Disease
Jan 2, 2026 l Hit 35
Current therapies for inflammatory bowel disease (IBD) often fail to achieve complete remission and are associated with systemic toxicity owing to their broad immunosuppressive effects. To overcome these limitations, we developed a bioengineered extracellular vesicle (EV) platform that modulates key immune signaling pathways to efficiently restore the T-cell balance in inflamed intestinal tissues. EVs derived from Wharton&r...
Airborne/Drone SIF Detection Technology Ushers in a New Era of Crop Stress Monitoring
Oct 6, 2025 l Hit 21
Sun-induced chlorophyll fluorescence (SIF) serves as a valuable indicator for remote sensing of plant physiology. Recent studies have shown that far-red SIF at 761 nm (hereafter SIF) from mid spectral resolution (SR) imagers (3–7 nm full width half maximum (FWHM)) derived reliable fluorescence emission in relative levels. Such mid SR based SIF (SIFMS; the subscript MS refers to mid SR basis) has been extensively utili...
